Your flat plate heat exchanger is leaking allowing the cold mains water at a higher pressure to leak into the boiler and CH system .That is why it is significantly higher when your run the hot tap as the cold water then circulates thro' the flat plate the boiler's own hot water is directed on a priority basis also thro' the exchanger but in its own seperate tube if there is a leak in the tube mains pressure enters the boiler water and hence the high pressure lifting the safety valve.
Guytawe, June 2010