It's highly possible that the drive have been accidently disabled.
When a drive, or any device, is disabled, it as if it was not even connected at all axcept that it appears in the devices manager.
From the controll pannel, start the "System" applet.
Sellect the devices management.
Any disabled device or any having any problem will show with a triangular yellow icon or octogonal red icon.
Find your external drive and double click on it. This brings it's properties.
If it have been deactivated, the button just above "Uninstall" should read "Activate".
Click that button.
Click OK.
You also may connect it to any other computer. That computer could be another PC running Windows, a Linux box or a Mac.
A disabled drive is disabled only on the computer from whitch it have been disabled. Any other computer can't "know" it have been disabled.
If there are any problem with the files or files system, Windows should propose you to analyse the drive to find and attempt to repair any problems.
You can also use any third party file recovery application.There are many available, several been free.
Whatever solution you chose, the recuperation process can take several hours.
Electro, July 2013