Like all things in life, what you need to do depends on other things.
If you have a system like those purchased from Dell, Gateway, etc., and it came with a "restore" disk, then you should save all your documents, pictures, etc, (the non-executable files) by copying them to a CD or to flash memory, or to a portable disk, then then use the restore disk to get your computer back to the "fresh from the factory" state.
Be forewarned that using the restore disk will wipe your hard drive completely, and put the files on the restore disk back on the drive. So, if you have installed any software in addition to what came with the computer, you want to make sure that you have the ability to reinstall it after you use the restore disk.
If you are not a techie, and don't want to take a chance on losing all your files, then I recommend contacting a local computer service firm that specializes in virus and adware removal. Make certain that they understand what files cannot be wiped from your hard drive if you have any critical stuff there. I caution you on this bacause many shops just wipe your hard drive clean without a thought, then do the restore, or reinstall from OEM software.
If your computer has a built-in restore function (typically on the D: drive), I would have to know when and how you used this before providing an answer. That is because you may have backed up everything - viruses, adware, spyware, etc., and will only restore them if you restore from the D: drive afater backing up your malicious software.
Robert, December 2006