are you talking about the copper hot water cylinder that stands in the cupboard ?
if so that the hot water for your tap's.
you will need to go in the loft and find the small plastic tank, and either turn off the water supply or tie up the ballcock.
or when you drain rads they will just keep filling.
when your ready to get system up and running again just turn on or release ballcock and the system will fill, bleed all rads and you should be ok.
sometimes depending on how system is piped the boiler,pump can get airlocked, but nothing to worry about.
hi-spec plumbing, July 2007